Nobel Prize in chemistry 2024 (Category PopularScience)

This year’s Chemistry Award also went in part to ML, which has helped in protein design:) Three people actually won.

• David Baker. A biochemist who worked in computational biology and won his part of the prize "for computational protein design"
• Demis Hassabis. and John Jumper Scientists who did ML at Google DeepMind and taught the machine to play Go (More in the "AlphaGo" documentary I'm talking about. told)computer games, as well as folding proteins (laying protein from a chain into a three-dimensional structure). In the end, 2020 In the same year, they introduced AlphaFold2, which was able to predict the structure of almost all of them. 200 millions of proteins identified by scientists.

In general, the Nobel Prize in Chemistry goes to scientists who have advanced the computational capabilities of mankind and with this were able to solve a fundamental problem. This is reminiscent of this year’s Physics Prize, which was given to scientists who have done much to advance deep learning. (deep learning)What do I mean? yesterday.

P.S. On the subject of the complexity of the problem of predicting the structure of proteins, you can read the popular science book by Grigory Nikiforovich.From orgasm to immortality. Drag designer notes"which I'm talking about." told. This book very easily tells about the relationship of amino acids, peptides and proteins. Peptides and proteins are composed of amino acids, but peptides are short chains and proteins are long. And peptides can often act as bioregulators. But the properties of these peptides and proteins depend not only on the sequence itself, but on their configuration in space, which can change under the influence of external conditions.

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